Abstract

Introduction: Migraine is the most common disabling primary headache. Depression is the leading cause of disability word wide. Depression is commonly seen as comorbid condition with migraine. The present study was done to look for prevalence of depression in migraineurs and also to look for impact on quality of life in those with comorbid migraine. Materials and methods: A case control study was done on 127 individuals with migraine and 30 age and sex matched healthy individuals. The International Headache Society's International Classification of Headache Disorders, 3rd Edition, (ICHD-III) was followed to diagnose Migraine with or without aura. Head ache impact test was used to assess severity of headache. Migraine disability assessment scale (MIDAS) was used to assess migraine related disability. Migraine disability assessment scale (MIDAS) was used to assess severity of migraine. Mini-International Neuropsychiatric Interview (M.I.N.I.) PLUS questionnaire was used to screen for the presence of depression. Hamilton Depression rating scale was used for assessing severity of depression. WHO Quality of Life -BREF questionnaire used to assess quality of life. Results: Depression was present in 31(24.4%) with migraine while none in control group had depression. In females depression was found in 28.08% while in males depression was found in 15.78%. Quality of life was significantly affected in those with depression. Conclusion: Depression is a common comorbid condition in migraine. Depression is more common in females with migraine. The longer acute headaches and higher migraine related disability are contributing factors for development of comorbid depression. Quality of life is also significantly affected in those with comorbid depression Perfect quality rolex replica watches UK are cheap online for men and women.
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